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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CEBPZ All Species: 23.94
Human Site: S621 Identified Species: 52.67
UniProt: Q03701 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q03701 NP_005751.2 1054 120988 S621 K A K P G L R S Q L D D H P E
Chimpanzee Pan troglodytes XP_001166712 1054 120897 S621 K A K P G L R S Q L D D H P E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_540150 1057 121074 S621 K A K P N L R S Q L D D H P E
Cat Felis silvestris
Mouse Mus musculus P53569 1052 120244 S621 K A K P D L R S Q L D D H P E
Rat Rattus norvegicus NP_001102171 1045 119794 S615 K A K P D L R S Q L D D H P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508935 1070 121303 T639 K V K P G L Q T Q L Q D H P E
Chicken Gallus gallus NP_001026231 1076 122572 V641 K V K P G L R V Q L Q D H V E
Frog Xenopus laevis NP_001088579 1006 114834 P590 Q V S C C Q K P S F I C G T L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19753 953 108405 L542 T T E K L V V L S K D I D P A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002331214 986 110072 S564 L L L R A M K S D I N L K R V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12176 1025 116658 S576 P F A Q I P A S V Y E V H M E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 N.A. 87.9 N.A. 82.3 82.2 N.A. 67.5 63 55 N.A. N.A. N.A. N.A. 30.8 N.A.
Protein Similarity: 100 99.1 N.A. 94.1 N.A. 90.3 90.6 N.A. 80.6 77.5 70.4 N.A. N.A. N.A. N.A. 50 N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. 73.3 73.3 0 N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. 86.6 73.3 13.3 N.A. N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: 32.3 N.A. N.A. N.A. 24.6 N.A.
Protein Similarity: 50.1 N.A. N.A. N.A. 44.7 N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. 20 N.A.
P-Site Similarity: 33.3 N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 46 10 0 10 0 10 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 10 10 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 0 0 0 0 19 0 0 0 10 0 55 64 10 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 73 % E
% Phe: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 0 0 37 0 0 0 0 0 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 73 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 10 10 10 0 0 0 % I
% Lys: 64 0 64 10 0 0 19 0 0 10 0 0 10 0 0 % K
% Leu: 10 10 10 0 10 64 0 10 0 64 0 10 0 0 10 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % N
% Pro: 10 0 0 64 0 10 0 10 0 0 0 0 0 64 0 % P
% Gln: 10 0 0 10 0 10 10 0 64 0 19 0 0 0 0 % Q
% Arg: 0 0 0 10 0 0 55 0 0 0 0 0 0 10 0 % R
% Ser: 0 0 10 0 0 0 0 64 19 0 0 0 0 0 0 % S
% Thr: 10 10 0 0 0 0 0 10 0 0 0 0 0 10 0 % T
% Val: 0 28 0 0 0 10 10 10 10 0 0 10 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _